NPM1–TYK2 mRNA transcript levels in Ba/F3–NPM1–TYK2 cells were compared to Myla cells (i.e., the only available NPM1–TYK2 endogenously expressing cell line) while the SU-DHL-1 (NPM1-ALK+ ALCL) T-cell lymphoma cell line served as a negative control (Fig. 1A)20. Here, TYK2 is linked to T-cell non-Hodgkin lymphoma.