The third strongest signal (OR = 4.9, P = 0.00001) in the deletion analysis for overall breast cancer was at 8: 132199447−132252439, 144Kb downstream of ADCY8. The strongest GWAS signal in this region lies in an intron of ADCY8 (lead SNP rs73348588, OR = 1.13, P = 8.2e−7)9. The gene discussed is ADCY8; the disease is breast cancer.