TGFB1 and cancer: Thorsson et al. presented immunogenomics analyses of more than 10,000 tumors in TCGA, identifying 6 immune subtypes (C1: wound healing, C2: IFN-γ dominant, C3: inflammatory, C4: lymphocyte depleted, C5: immunologically quiet, C6: TGF-β dominant) that encompass 33 cancer types based on six key signatures25.