Targeted sequencing of 54 genes (a list of the tested mutations can be found in Supplementary Table 1) commonly affected in MDS was performed for 10 MDS samples, providing the number of mutations (range, 0–8; ASXL1, KRAS, NRAS, CEBPA, SRSF2, CBL, TET2, ZRSR2, EZH2, BCOR, DNMT3A, IDH2, RUNX1, PTPN11, SF3B1, WT1). The gene discussed is EZH2; the disease is myelodysplastic syndrome.