The LV ECVF (β = −.281, P = 0.049), LVEF (β = .455, P = 0.002), cardiac V10Gy (β = −.330, P = 0.006), and NTproBNP (β = −.319, P = 0.013) were retained in the model as independent predictors of %O2Pulse while cancer type was removed from the model. This evidence concerns the gene NPPB and cancer.