TFE3 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: As a well-known and famous oncogene, MET plays an important role in cancer etiology, and there have been a few studies that have examined the high protein level of MET in Xp11.2 tRCC [21], including NONO-TFE3 tRCC.