TFE3 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: In the present study, Xp11.2 translocation/NONO-TFE3 fusion renal cell carcinoma (NONO-TFE3 tRCC) with up-regulated CircMET was employed to investigate its mechanism in cancer progression and post-transcriptional regulation.