In search of SLE anti-cardiolipin IgM and IgG antibodies, Beta-2 glycoprotein 1 IgG and IgM antibodies, and lupus anticoagulant were negative; however, anti-double-stranded deoxyribonucleic acid anti-Smith antibodies were positive, as well as Complement C3 and C4 were decreased (Table 2). The gene discussed is CD40LG; the disease is systemic lupus erythematosus.