Similarly, Alexander et al. (18) showed increased ST6GAL-1 expression in gastric premalignancy and adenocarcinoma, that ST6GAL-1 overexpression enhances resistance to TNF-induced epithelial cell apoptosis, and that ST6GAL-1 overexpression dysregulates apoptosis in gastric cancer. Here, ST6GAL1 is linked to adenocarcinoma.