Furthermore, we found a strong positive correlation between resting P-selectin exposure and GPVI-dimer expression in resting platelets of the stroke cohort (Fig 2B), similar to what had been demonstrated previously in coronary artery disease patients by Loyau et al. [25] In the controls, a positive relationship was also observed, although P-selectin expression was much lower. Here, GP6 is linked to coronary artery disorder.