We infected the human renal carcinoma cell line iSLK [33,34] with a modified version of the BAC16 KSHV genome containing a far-red fluorescent protein (mIFP2) driven by the promoter of the viral late gene K8.1 as well as a constitutive EGFP (S1A Fig). The gene discussed is ENSG00000280371; the disease is renal carcinoma.