Comparison of the clinicopathologic characteristics between Laurén subtypes demonstrated that Laurén mixed tumors were more similar to diffuse-type tumors in some domains (more advanced pT and pN stage, similar low rates of HER2 positivity) and were more comparable with intestinal-type tumors in others (lower margin positivity, higher LVI rates, less tumor recurrence and better survival). The gene discussed is ERBB2; the disease is neoplasm.