OIP5‐AS1's regulation of miR‐410 activity contributes to regulation of the KLF10/PTEN/AKT signalling pathway, where PTEN/AKT is downstream of miR‐410 activity, while KLF10 and OIP5‐AS1 action to regulate miR‐410 result in decreased cell proliferation while inducing apoptosis, characterising both as downstream mediators in multiple myeloma progression.129. The gene discussed is PTEN; the disease is plasma cell myeloma.