As shown in Figure 1, significantly higher transcriptional levels of EIF3A/ B/ C/ E/ H/ I/ J/ M and lower transcriptional levels of EIF3D/ F/ G/ L in breast cancer compared to para-carcinoma tissues (Figure 1(a), p < 0.001) and TCGA both indicated significantly higher expression of EIF3B/ C/ H/ I/ J and lower EIF3D/F /L in breast cancer tissues (Figure 1(b-l), P < 0.001). The gene discussed is EIF3A; the disease is breast cancer.