We evaluated prediction accuracies for prostate cancer using the following data sets: still ultrasound image data (left upper box), clinical data (age and prostate-specific antigen [PSA]) (right upper box), and integrated data (ultrasound image data, total prostate volume [TPV] derived from ultrasound images, PSA density [PSAD], age, and PSA) (lower box). This evidence concerns the gene KLK3 and Familial prostate cancer.