In a previous analysis in MESA that used a candidate gene approach to assess the association between CpGs in AHRR and atherosclerosis, hypomethylation at cg05575921 (P = 3.08 × 10−10) and cg21161138 (P = 7.73 × 10−8) was significantly associated with carotid plaque score [61]. Here, AHRR is linked to atherosclerosis.