According to TCGA dataset, the methylation levels of SLCO4A1-AS1 in CRC tissues were markedly lower than those in NCTs and were negatively correlated with the expression levels of SLCO4A1-AS1 in CRC tissues from both TCGA and CCLE data sets (Fig. 2b–d, Additional file 5: Table S4). Here, SLCO4A1 is linked to colorectal carcinoma.