FNDC5 and myocardial infarction: BM‐MSCs with FNDC5 overexpression improved the survival of transplanted BM‐MSCs, which significantly reduced fibrosis and alleviated injured heart function in a mouse MI model.[46] The final outcome, that is, enhanced cardioprotective ability of FNDC5/irisin pretreated MSCs is the same, demonstrating the reproducibility of our experimental finding.