Furthermore, primary immunodeficiency, cytokine‐cytokine receptor interactions and the TGF‐beta signaling pathway were altered in OPCs; ECM receptor interactions, proteoglycans in cancer, and focal adhesion were altered in BLA‐Exc neurons; and the TNF signaling pathway, Toll‐like receptor signaling pathway and ErbB signaling pathway were altered in BLA/CeA‐Inhib neurons. The gene discussed is TGFB1; the disease is cancer.