SPP1 and breast carcinoma: The percentages of high protein expression of CD24, SDC1, and SPP1 were 28.6, 34.2, and 19.2% in breast cancer tissue, compared with 1.5, 1.5, and 1.1% in pan-cancer tissue, respectively (P=0.00, P=0.00, and P=0.00) (Table 8, Figure 5B).