For example, METTL3 increased m6A modification of PCAT6, resulting in PCAT6 upregulation in an IGF2BP2-dependent manner [38]; LCAT3 stability was significantly increased in a METTL3-dependent manner in lung adenocarcinomas, thereby activating MYC transcription via FUBP1 [39]. The gene discussed is IGF2BP2; the disease is lung adenocarcinoma.