METTL3 and hepatocellular carcinoma: In-depth mechanism research revealed that LINC01273 was co-located with miR-600 in the cytoplasm of HCC cells, LINC01273 increased miR-600 stability via acting as a ‘reservoir’, enhancing the repressive effect of miR-600 on METTL3 mRNA, resulting in METTL3 downregulation, thereby conferring the sorafenib resistance of HCC cells.