Two FA genes, FANCD2/I, are consistently associated with PICH‐positive UFBs, suggesting a possible functional interaction between PICH and FANCD2/I.[53] We would suggest a further investigation of the role of dsDNA‐cGAS‐type I IFN axis in the pathogenesis of FA is warranted. The gene discussed is CGAS; the disease is Friedreich ataxia.