CRTC2 and autosomal dominant polycystic kidney disease: Immunofluorescence analysis in these cells showed that TY1‐WT‐CRTC2 exhibited nuclear puncta staining, whereas the TY1‐CRTC2‐R>A mutant showed diffuse staining, supporting the idea that R>A mutation in CRTC2 disrupts its ability to form condensates in ADPKD cells (Figure 8d).