Among lncRAP2 interactors, Igf2bp2 regulates adipocyte function via posttranscriptional control of metabolically important proteins, impacting sensitivity to diet-induced obesity and type 2 diabetes risk (Dai et al., 2015; Laggai et al., 2014; Zhang et al., 2018). This evidence concerns the gene IGF2BP2 and type 2 diabetes mellitus.