IGF2BP2 and obesity due to melanocortin 4 receptor deficiency: Among lncRAP2 interactors, Igf2bp2 regulates adipocyte function via posttranscriptional control of metabolically important proteins, impacting sensitivity to diet-induced obesity and type 2 diabetes risk (Dai et al., 2015; Laggai et al., 2014; Zhang et al., 2018).