The plasmacytoma variant translocation 1 (PVT1) is located at cancer risk region 8q24.21 [7], which has been identified to aberrantly expressed in various cancers including pancreatic [8], prostate [9, 10], bladder [11] cancers, and hepatocellular carcinoma [12]. The gene discussed is PVT1; the disease is hepatocellular carcinoma.