DOK5 and metastatic malignant neoplasm in the lymph nodes: It is worth noting that among patients with lymph node metastasis, patients with high DOK5 expression have a poorer prognosis (OS: stage N1, HR = 2.43, P < 0.001; stage N2, HR = 1.78, P < 0.05; stage N3, HR = 1.88, P < 0.05; stage N1+2+3, HR = 1.97, P < 0.001.