MRP1 is also reported to be a major player in the regulation of several physiological processes like redox homeostasis, steroid metabolism, tissue defense, and the etiology of neurodegenerative and cardiovascular diseases (Ballatori et al., 2009a; Ballatori et al., 2009b; Cole, 2014; Krohn et al., 2011; Leslie, Deeley & Cole, 2005; Long, Li & Cui, 2011; Park et al., 2011; Sivils, Gonzalez & Bain, 2010). Here, ABCC1 is linked to cardiovascular disorder.