Further analysis of The Cancer Genome Atlas (TCGA) data revealed that ZFAS1 was upregulated in CRC among the six digestive system tumors esophageal carcinoma (ESCA), esophageal carcinoma (STAD), colon adenocarcinoma (COAD), cholangio carcinoma (CHOL), pancreatic adenocarcinoma (PAAD), and liver hepatocellular carcinoma (LIHC) (Figure 1B). The gene discussed is ZFAS1; the disease is digestive system neoplasm.