CRP and obesity due to melanocortin 4 receptor deficiency: Elevation of CRP levels can take two forms: a rapid, acute rise usually associated with a current infection or injury, or a persistent, low-grade elevation linked to conditions including obesity [4], especially visceral adiposity [5, 6], metabolic disorders, including cardiovascular diseases (CVDs) [4, 7] and type 2 diabetes mellitus (T2DM) [8, 9].