Another study found that puerarin's regulatory effect on TGF‐β/Smad and ERK1/2 signaling pathway may also be one of the strategies for alleviating liver fibrosis, which brings hope for the treatment of liver fibrosis (Xiuqing Li et al., 2019; Xu et al., 2013). Here, TGFB1 is linked to Hepatic fibrosis.