Moreover, the activated mTORC1 pathway had oncogenic roles in NSCLC [33], and our results also indicated that the regulation of the mTORC1 pathway by the LDLRAD3-miR-20a-5p-SLC7A5 axis was associated with malignant behaviors of NSCLC cells. This evidence concerns the gene SLC7A5 and non-small cell lung carcinoma.