The results of immunohistochemical staining (Figures 2(a)–2(c)), Western blot (Figure 2(d)), and RT-PCR (Figure 2(e)) showed that MTMR14 was extensively expressed in the lung tissues of mice, in particular in the bronchial epithelium, while the expression of MTMR14 was significantly decreased in COPD mice. The gene discussed is MTMR14; the disease is chronic obstructive pulmonary disease.