In the CHD specimens and the TBX1-silenced, miR-193a-3p-inhibited, and TGF-β2-overexpressing H9c2 cells, the downregulated protein expression of NRF2, GPX4, and HO-1 and the upregulated protein expression of NOX4 and ACSL4, as well as the elevated lipid ROS levels, MDA levels, Fe2+ concentrations, and mitochondrial ROS levels, confirm that ferroptosis is involved in the occurrence of CHD (Figures 3(d)–3(f), 3(h)–3(i), 4(a)–4(e), 5(a)–5(e), and 7(a)–7(h)). This evidence concerns the gene TGFB2 and coronary artery disorder.