NOX4 and coronary artery disorder: In the CHD specimens and the TBX1-silenced, miR-193a-3p-inhibited, and TGF-β2-overexpressing H9c2 cells, the downregulated protein expression of NRF2, GPX4, and HO-1 and the upregulated protein expression of NOX4 and ACSL4, as well as the elevated lipid ROS levels, MDA levels, Fe2+ concentrations, and mitochondrial ROS levels, confirm that ferroptosis is involved in the occurrence of CHD (Figures 3(d)–3(f), 3(h)–3(i), 4(a)–4(e), 5(a)–5(e), and 7(a)–7(h)).