Besides, the measured results also revealed that compared with the normal group, the GDM group exhibited a marked reduction in the serum 25-OH-D and BMD levels and a substantial increase in the BALP, OC, PINP, and β-CTx levels, conforming with the findings reported in other studies.11,12 This indicates that in pregnant women with GDM, increased blood glucose is associated with the decreased expression of 25-OH-D, which reduces BMD and leads to bone metabolism disorders. This evidence concerns the gene BGLAP and metabolic bone disorder.