Van Eijk and Eijkemans [6] recently demonstrated that genotypic data for unc-13 homolog a (UNC13A), myelin-associated oligodendrocyte basic protein (MOBP), and the repeat expansion in c9orf720-SMCR8 complex subunit (C9orf72) could influence both primary and secondary outcomes including survival, ALS functional rating scale (ALFSRS) and forced vital capacity (FVC) measures. This evidence concerns the gene C9orf72 and amyotrophic lateral sclerosis.