The IgG, TBIL, prothrombin time (PT), ferritin, and TSI in the advanced fibrosis group were significantly higher than those in the nonadvanced fibrosis group (P < 0.05), while the ALB, platelet (PLT) count, transferrin, UIBC, and TIBC in the advanced fibrosis group were significantly lower than those in the nonadvanced fibrosis group (P < 0.05). The gene discussed is F2; the disease is fibrosis.