CCK8 assays showed that overexpression of ADORA2A-AS1 significantly promoted cell proliferation, while miR-665 mimic inhibited cell viability and partially attenuated the pro-proliferative effect of ADORA2A-AS1 in CML cells (Figure 5(b)). The gene discussed is ADORA2A; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.