Siniscalco et al. found that hMSCs delivered systemically via the tail vein decrease secretion levels of IL-1β and IL-17 and increase expression levels of IL-10 and the CD206 macrophage marker in a mouse model of neuropathic pain, thus the authors concluded that T lymphocytes are associated with the production of pro-inflammatory cytokines IL-17 and IL-1β [75]. The gene discussed is IL1B; the disease is neuropathic pain.