NCEH1 mRNA expression was lower whereas LIPE mRNA expression was higher in metastatic prostate cancer tissue compared to primary tissue (Fig. 4c and d); however, the protein levels of nCEH1 were increased in metastatic CRPC tissue compared to benign and primary cancer tissue, while HSL protein was not reported/detected (Fig. 4e). This evidence concerns the gene LIPE and prostate cancer.