For example, in patients with colorectal cancers, exosomal miRNAs extracted from sera showed higher sensitivity (90%) in comparison to carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) serum biomarkers with 30.7% and 16% sensitivity, respectively [165]. Here, CEACAM5 is linked to colorectal cancer.