FGF2 and cancer: Interestingly, malignant tumor cells can partially express Fibrinogen [4].Fibrinogen has also been associated with vascular endothelial cell growth factor (VEGF) and fibroblast growth factor 2 (FGF-2) and can promote tumor cell adhesion, proliferation and migration [5].Elevated serum fibrinogen levels are usually associated with poor prognosis of human cancers [6, 7].