Among the 19 candidate genes, 19 genes AURKA, NCAPG, CCNA2, TPX2, TOP2A, KIF20A, MELK, TRIP13, KIF2C, PRC1, ASPM, TKIF4A, CENPF, CDC20, PTTG1, CDCA5, TK1, MCM2, HJURP are high in HCC Express. The gene discussed is MELK; the disease is hepatocellular carcinoma.