Four ASXL1 variants were identified in this study, of which, the ASXL1 p.Gly646Trpfs*10 (c.1927_1928insGGGGGGGGTGGCCCGGGTGGAGGTGGCGGCGGGGCCACCGATGAGGGGGGGGGCAGAGGCAGCAGCA) stopgain variant (Sample 04, PV) was found to be located in the same dbSNP cluster rs750318549 as the previously reported ASXL1 p.Gly646Trpfs*12 (c.1934dupG) stopgain, which is the most common ASXL1 mutation accounting for > 50% of all identified ASXL1 mutations in myeloid malignancies [19] (Table 2). The gene discussed is ASXL1; the disease is myeloid neoplasm.