Of note, Sample 02 was found to carry another TET2 variant—the p.Tyr1631* stopgain, reported as pathogenic in the COSMIC database and previously identified in angioimmunoblastic T cell lymphoma [33], CML, and AML [34] at a VAF of 1.4% (Table 2). Here, TET2 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.