For example, in the most studied breast cancer, CARM1 could methylate the R838 site of lysine demethylase 1 (LSD1) to promote the binding of deubiquitinase USP7, resulting in the ubiquitination and stabilization of LSD1, thereby promoting the invasion and metastasis of breast cancer cells [16]. The gene discussed is CARM1; the disease is breast carcinoma.