CARM1 and pancreatic adenocarcinoma: As shown in Fig. 6a, there is a positive correlation between CARM1 expression and TMB for LUAD (P = 0.00031), pancreatic adenocarcinoma (PAAD, P = 0.049), SARC (P = 0.0067), BRCA (P = 0.0013), STAD (P = 8.3e-07), SKCM (P = 0.021), HNSC (P = 0.0059), LGG (P = 4.1e-06) and ACC (P = 0.0038), but a negative correlation for KIRP(P = 0.032), LIHC (P = 0.036), THCA (P = 0.00022).