CD40 and Schnyder corneal dystrophy: We validated the scRNA-seq data across multiple mice by qRT-PCR analysis of enriched DCs from eight control and eight SCD animals, which revealed profound suppression of the signals for Cd74, H2-Ab1, and the DC maturation markers Cd83, Ccr7, and Cd40 in the SCD mouse spleens compared with the spleens of control littermates.