There have been no published reports on a role for BCOR in lipid metabolism, but loss of BCL6 in the liver augments lipid catabolism, lessens high-fat-diet induced hepatic steatosis, and reverses fatty acid breakdown and lipid accumulation induced by fasting in peroxisome proliferator activated receptor alpha (Ppara) knockout mice29. The gene discussed is PPARA; the disease is fatty liver disease.