RAC1 and lung cancer: The proliferation ability of LLC was significantly inhibited by NSC23766 at basal condition (before radiation), and this inhibitory effect was further intensified after radiation (P < 0.001, Fig. 7C, D), while that of MLE-12 was little affected (P > 0.05, Fig. 7C, D), indicating that the proliferation of lung cancer cells was more dependent on Rac1.