It was shown that exosomes isolated from EOC tumor explant and EOC cell-line culture supernatants, and ascitic fluid from EOC patients differentially and constitutively express NKG2D ligands from both MICA/B and ULBP families on their surface, while DNAM-1 ligands are more seldom expressed and not associated with the exosomal membrane surface [84]. This evidence concerns the gene KLRK1 and neoplasm.