EZH2 and gastric cancer: Xuan et al. revealed that SNHG3 recruited enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2) to the promoter region of mediator complex subunit 18 (MED18), which significantly decreased the expression of MED18 via methylation regulation, further increasing the metastatic properties of gastric cancer cells [45].