GLB1 and GM1 gangliosidosis: The hotspot regions for GLB1 mutations appear to cluster in exons 2, 6, and 15.[12] Korean patients with GM1 gangliosidosis have the most common mutation of p.D448 V in exon 13.5 However, our patient had 2 known mutations [c.601C> T (p.Arg201Cys) and c.574T> C (p.Tyr192His)] in exon 7 of GLB1.