In-depth assessment of any patients with lumbar intraspinal gout tophus should contain a detailed disease history and comprehensive physical examination, since these individuals most commonly have an extensive history of alcoholism, hyperuricemia, chronic gout, or renal insufficiency.[5,10] Among them, the white blood cell count, erythrocyte sedimentation rate, C-reactive protein, and serum uric acid levels are usually elevated,[3,5,10] which may further provide the diagnostic possibilities of gout tophus previously not considered. The gene discussed is CRP; the disease is Renal insufficiency.